Skip To Main Content

COVID-19 Updates and Resources. Learn More

Meta-Analysis of Prospective Cohort Studies Evaluating the Association of Saturated Fat with Cardiovascular Disease

The following information is available at Pub Med and was not written by Atkins professionals.

American Journal of Clinical Nutrition

Siri-Tarino, P.W., Sun, Q., Hu, F.B., Krauss, R.M., “Meta-Analysis of Prospective Cohort Studies Evaluating the Association of Saturated Fat with Cardiovascular Disease,"American Journal of Clinical Nutrition, 2010, Jan. 13.

BACKGROUND:

A reduction in dietary saturated fat has generally been thought to improve cardiovascular health.

OBJECTIVE:

The objective of this meta-analysis was to summarize the evidence related to the association of dietary saturated fat with risk of coronary heart disease (CHD), stroke, and cardiovascular disease (CVD; CHD inclusive of stroke) in prospective epidemiologic studies.

DESIGN:

Twenty-one studies identified by searching MEDLINE and EMBASE databases and secondary referencing qualified for inclusion in this study. A random-effects model was used to derive composite relative risk estimates for CHD, stroke, and CVD. RESULTS: During 5-23 y of follow-up of 347,747 subjects, 11,006 developed CHD or stroke. Intake of saturated fat was not associated with an increased risk of CHD, stroke, or CVD. The pooled relative risk estimates that compared extreme quantiles of saturated fat intake were 1.07 (95% CI: 0.96, 1.19; P = 0.22) for CHD, 0.81 (95% CI: 0.62, 1.05; P = 0.11) for stroke, and 1.00 (95% CI: 0.89, 1.11; P = 0.95) for CVD. Consideration of age, sex, and study quality did not change the results.

CONCLUSIONS:

A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD. More data are needed to elucidate whether CVD risks are likely to be influenced by the specific nutrients used to replace saturated fat.

PMID: 20071648 [PubMed - as supplied by publisher]

Try Keto – The Atkins® Way

Atkins keto plans are more flexible and more personalized to provide a long-term plan for reaching your goals. Our free tools can help you even further.

Get Started

Learn More AboutArticles

How To Make Low Carb Crockpot Recipes this Winter

Less time spent cooking this winter means more time to yourself.

Lire la suite »

Low Carb Mother's Day Brunch Ideas & Recipes

For all the work they do, it seems crazy that mothers only get one day a year.

Lire la suite »

National Pomegranate Month

There are plenty of reasons to eat pomegranate.

Lire la suite »

Low Carb Halloween Recipes & Recipe Ideas

Halloween is scary—especially when you’re on a low carb diet and surrounded by candy with nowhere to escape.

Lire la suite »

This site uses essential cookies to function. It also uses non-essential cookies for marketing and advertising. For more information please see ourPrivacy Policy.

This site uses essential cookies to function. It also uses non-essential cookies for marketing and advertising. For more information please see ourPrivacy Policy.

Close button